Initial Combination of Empagliflozin and Metformin in Patients With Type 2 Diabetes
نویسندگان
چکیده
منابع مشابه
Initial combination of empagliflozin and linagliptin in subjects with type 2 diabetes.
OBJECTIVE To evaluate the efficacy and safety of empagliflozin/linagliptin in subjects with type 2 diabetes. RESEARCH DESIGN AND METHODS Subjects not receiving antidiabetes therapy for ≥12 weeks were randomized to empagliflozin 25 mg/linagliptin 5 mg (n = 137), empagliflozin 10 mg/linagliptin 5 mg (n = 136), empagliflozin 25 mg (n = 135), empagliflozin 10 mg (n = 134), or linagliptin 5 mg (n ...
متن کاملInitial combination therapy for patients with type 2 diabetes mellitus: considerations for metformin plus linagliptin
For patients with type 2 diabetes mellitus, management of hyperglycemia is typically complex, and few patients successfully achieve and maintain recommended targets for glycated hemoglobin (HbA1c). Increasingly, combination therapy is recommended early in the disease course, or even directly at diagnosis in patients with relatively high HbA1c levels. A recent randomized, placebo-controlled, Pha...
متن کاملEmpagliflozin as Add-on to Metformin Plus Sulfonylurea in Patients With Type 2 Diabetes
OBJECTIVE To investigate the efficacy and tolerability of empagliflozin as add-on to metformin and sulfonylurea in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS Patients inadequately controlled on metformin and sulfonylurea (HbA1c ≥7 to ≤10%) were randomized and treated with once-daily empagliflozin 10 mg (n = 225), empagliflozin 25 mg (n = 216), or placebo (n = 225) for 24 weeks...
متن کاملEffect of Empagliflozin on Electrolytes and Lipid Profiles in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis
Introduction: Studies examining the effect of Empagliflozin in patients with type 2 diabetes have reported different results regarding the effect of this drug on electrolytes and lipid profiles. This study aimed to evaluate the effect of Empagliflozin on electrolytes and lipid profiles in patients with type 2 diabetes. Materials and Methods: In this systematic meta-analysis, clinical trials pub...
متن کاملCombination of empagliflozin and linagliptin as second-line therapy in subjects with type 2 diabetes inadequately controlled on metformin.
OBJECTIVE To evaluate the efficacy and safety of combinations of empagliflozin/linagliptin as second-line therapy in subjects with type 2 diabetes inadequately controlled on metformin. RESEARCH DESIGN AND METHODS Subjects were randomized to a combination of empagliflozin 25 mg/linagliptin 5 mg (n = 137), empagliflozin 10 mg/linagliptin 5 mg (n = 136), empagliflozin 25 mg (n = 141), empagliflo...
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ژورنال
عنوان ژورنال: Diabetes Care
سال: 2016
ISSN: 0149-5992,1935-5548
DOI: 10.2337/dc16-0522